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Image Search Results
Journal: PLoS ONE
Article Title: Gene Expression Commons: An Open Platform for Absolute Gene Expression Profiling
doi: 10.1371/journal.pone.0040321
Figure Lengend Snippet: (A) Relative vs. absolute gene expression profiling. Conventional methods compare differences in gene expression between samples within an individual experiment, and result in relative values only (left). In Gene Expression Commons, raw microarray data is individually normalized against a large-scale common reference, then mapped onto the probeset meta profile. This strategy enables profiling of absolute expression levels of all genes on the microarray (right). (B) Relationship between the size of the common reference and the accuracy of the probeset dynamic range estimation. The result of one out of five experiments is shown. The Y-axis represents % probesets with false estimation of dynamic range in mean ± S.E.M (n = 10). (C) The dynamic range versus the mean of each probeset in Affymetrix Mouse 430 2.0 (n = 11,939) (left) and Affymetrix Human U133 Plus 2 (n = 25,229) (right) presented by a density plot and histograms. (D) Graphical representation of probeset meta profile. The Y-axis represents expression intensity without units in log2 scale. The distribution of expression levels is displayed by a histogram (right side of the axis). The high/low threshold computed is shown by a solid bar, and the distribution of percentiles in either the high or low expression range is indicated by a gradation of color, displayed as highest (+100%) in dark red, threshold (0%) in white, lowest (−100%) in dark blue (left side of the axis). Four diverse distributions of probesets for four different genes (Aak1, Rbx1, Hif1a and Ikzf1) (left), and diverse distribution of four probesets of one gene (Il16) (right) are shown.
Article Snippet: We downloaded 11,939 Affymetrix Mouse Genome 430 2.0 and 25,299
Techniques: Expressing, Microarray
Journal: PLoS ONE
Article Title: Gene Expression Commons: An Open Platform for Absolute Gene Expression Profiling
doi: 10.1371/journal.pone.0040321
Figure Lengend Snippet: Size of universal reference and probeset dynamic-range estimation Affymetrix Human U133 Plus 2 (54677 probesets).
Article Snippet: We downloaded 11,939 Affymetrix Mouse Genome 430 2.0 and 25,299
Techniques:
Journal: Journal of Applied Physiology
Article Title: Impact of brief exercise on peripheral blood NK cell gene and microRNA expression in young adults
doi: 10.1152/japplphysiol.01341.2012
Figure Lengend Snippet: Comparison of microarray and RT-PCR gene expression data
Article Snippet: We used Affymetrix U133+2.0 arrays for gene expression and
Techniques: Microarray, Expressing
Journal: BMC Systems Biology
Article Title: Vascular endothelial growth factor A as predictive marker for mTOR inhibition in relapsing high-grade serous ovarian cancer
doi: 10.1186/s12918-016-0278-z
Figure Lengend Snippet: Clinical characteristics of samples and classifier performance
Article Snippet: array platform , Affymetrix Human Genome U133 Plus 2.0 ,
Techniques: Microarray